Strontium Ranelate and bone healing: report of two cases.

Introduction There are several factors influencing the fracture healing process, the most important being age and bone quality. Cellular and molecular alterations that can be found in elderly patients make the healing process difficult, and may lead to complications such as pseudoarthrosis or delayed non-union. In the same way, in altered bone metabolism condition such as osteoporosis, physiological phases of fracture healing are impaired. Due to the wide availability of anti-osteoporotic drugs whose primary end-points are to improve BMD and to reduce fracture risk, the secondary end-point of these drugs is now focused on their possible use on fracture healing deficiency conditions.